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Yahoo has just launched its new Ads for Adobe PDF program, which will allow publishers to display contextual pay-per-click ads in a panel adjacent to the content within PDFs.
Details can be found on the official Ads for Adobe PDF blog.
I think this is a good opportunity for writers to monetize their content while keeping it free for their readers. For example, this new service allows the integration of ads into eBooks or scientific reports published online.
It is my understanding that the service is only available to a limited number of publishers at this time. But if you’re interested, you can apply here.



Here is a link to a preliminary (but complete) review of this program. Definitely a good Beta effort by the Adobe team, but still a work in progress. Bottom line, it is worth trying:
http://www.qzaki.com/Archive/AdsforPDF-Review.pdf